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Today's Science is Not a Cautionary Tale

Friday, January 19, 2018

Today‚Äôs Friday Pearl addresses a study featured in the January 2017 journal, Aging, because we think better understanding nitric oxide and curcumin science is important for eye and body health.

Thirty-nine healthy men and-post menopausal women aged 45 to 74 years were randomized to 12 weeks of supplemental curcumin (2,000 mg per day) or placebo.

In healthy middle-aged and older adults this study found that 12 weeks of curcumin supplementation improved resistance artery endothelial function (blood flow) by increasing vascular nitric oxide bioavailability and reducing oxidative stress, while also improving conduit artery endothelial function (ability to stretch in response to each pulse).

Nitric oxide is a signaling molecule produced by the endothelial cells lining the arteries that penetrates the underlying smooth muscles and acts as a potent vasodilator that relaxes the arteries. 

Curcumin has also been used in India as a spice, as a food preservative and for health care for centuries. It has been clinically suggested to exhibit antioxidant, anti-inflammatory, antiviral, antifungal and antibacterial activities associated with a number of structure / function health issues.
This new study adds to the ever-growning body of evidence suggesting multi-targeted therapy may prove to be better than mono-targeted prescription drug therapy for a number of health problems.

Curcumin and the retina

An original research study published in Drug Design, Development and Therapy looked at the effect of curcumin on aging retinal pigment epithelial cells.

The investigators reported that in the aging state, curcumin significantly improved cell viability by regulating oxidative stress, apoptosis, and decreasing intracellular reactive oxygen species (ROS) when compared with the control group.

Other studies suggest that curcumin may be an efficient vascular endothelial growth factor (VGEF) blocker similar to the drugs now being injected into the eye.

This information may prove to be particularly important to protect against changes associated with age-related eye health.

Curcumin consumption: blood lipids and glucose levels

An interesting study for those of you who also love curries was published in the April 2016 Nutrition Research Practice using data obtained from the Korean National Health and Nutrition Examination Survey to assess curry consumption frequency as well as blood glucose and blood lipid levels.  

Most curries include a moderate amount of curcumin, or turmeric, spice.

The blood glucose and triglyceride levels were significantly lower in the moderate curry consumption group compared to the low curry consumption group.

Ellen Troyer with Spencer Thornton, MD, David Amess, and the Biosyntrx staff


We do not believe curcumin or nitric oxide science should be viewed as a cautionary tale because the vast amount of published medical curcumin literature supports healthy human body structure / function activity. The only reason it is not included in our multiple, Eye & Body Complete is space constraint. We strongly recommend a high quality concentrated curcumin called CurcuWin. FDA nutritional supplement regulatory law prevents us from including direct purchase links in our science-based educational Friday Pearls.

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