Friday Pearls

Friday Pearls

How Does the Genomics Revolution Affect the Eye Care Professional?

Friday, June 22, 2007

"Nearly every ocular disease has a genetic component. That’s why genomics and molecular biology are changing the way eye disease is diagnosed and treated. Gene-based approaches will play a prominent role in disease prevention in the future." Charles Wormington, O.D. PhD, Associate Professor of Biophysics and Optometry, Pennsylvania College of Optometry.

Age Related Macular Degeneration: The First Year

Friday, June 15, 2007

The June 2007 issue of Archives of Ophthalmology reviews the recently published book, The First Year: Age-Related Macular Degeneration: An Essential Guide for the Newly Diagnosed, by Dan Roberts - the visually impaired founder of MD Support.

LAST II: Responders vs. Nonresponders

Friday, June 08, 2007

The objective of Stuart Richer, OD, PhD's original Lutein Antioxidant Supplementation Trial (LAST) was to determine whether specific dietary interventions increased macular pigment optical density (MPOD) and visual function in patients with atrophic age-related macular degeneration (ARMD). His objective with the recent LAST II study was to discern which of the specific characteristics that increase MPOD differentiate a supplement responder from a nonresponder.

Randomized Clinical Trials and Micronutrients

Friday, June 01, 2007

Scientists are being asked to consider whether the drug model for research relying strictly on randomized clinical trials (RCTs) is actually the most appropriate evidence-based research model for nutrients, including dietary supplements.

Silent Spring

Friday, May 25, 2007

"There was once a town in the heart of America where all life seemed to live in harmony with its surroundings." First sentence, Rachel Carson's Silent Spring   The book took its title from the opening chapter, a vision of a rural community rendered silent in springtime - its habitual birdsong silenced by the mass poisoning of all the birds. 

Multivitamin Use and Risk of Prostate Cancer

Friday, May 18, 2007

A study published in the May 16 Journal of the National Cancer Institute (JNCI) on “Multivitamin Use and Risk of Prostate Cancer in the National Institutes of Health–AARP Diet and Health Study” concludes that there was no association observed between multivitamin use and risk of localized prostate cancer. However, the researchers found an increased risk of advanced and fatal prostate cancers among men reporting excessive use of multivitamins (more than seven times per week) when compared with never users.

Proteomics, Exercise and Inflammation

Friday, May 11, 2007

Today’s column addresses questions from our recent ASCRS Eyes on Fire lecture. Proteomic science is changing the way many gerontologists think about inflammation, the aging process and degenerative diseases. The term proteomics was coined as an analogy to genomics, the study of genes. Understanding the structure and function of each protein and the complexities of protein-protein interactions is becoming critical to the development of effective diagnostics, disease treatments and more importantly, degenerative disease prevention including eye disease.  

Genomics, Nutrition & Inflammation

Friday, May 04, 2007

Our genes are formed from microscopic double-strands of deoxyribonucleic acid (DNA). They are dependent on adequate nutrition for their structure and activity. By appropriately switching on and off (this is called transcription in the genome research world) our genes direct the behavior of our body's 60 trillion cells. Many genetic researchers consider our genes to be the Rosetta stone of health and disease.

On Conjecture and Theorems

Tuesday, May 01, 2007

A reclusive Russian mathematician, Grigori Perelman, used the equations of Ricci flow (a process by which topological regions of high curvature flow into regions of lower curvature) to finally prove the daunting 100 year old Poincare Conjecture - arguably one of the most famous unsolved math problems in the world.

Innovation: The Pain, The Pleasure

Friday, April 27, 2007

Robert Stegmann, MD, discussed the pain and the pleasure of living an innovative life as a surgeon when he was awarded the "Sir Harold Ridley Distinguished Visiting Professorship for Creativity and Innovation in Ophthalmology," by Jerre Freeman, MD and Barrett Haik, MD, of the Department of Ophthalmology at the University of Tennessee, Memphis on Wednesday, April 25th, 2007.

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