Friday, March 10, 2006
There is considerable scientific evidence that suggests age-related disease is associated with a reduced ability to cope with physiological challenges. One of the roles of the amino acid, carnitine, is to assist the physiological transport of long-chain essential fatty acids (think Omega-3s) across mitochondrial membranes. This facilitates fatty acid energy production and the transport of reactive oxygen species (ROS) compounds out of the mitochondria, preventing their toxic accumulation.
Friday, March 03, 2006
Long term epidemiological studies suggest oxidative stress from environmental factors like smoking and sunlight exposure, as well as low dietary intake of antioxidants, to be the major contributing factors in the development of age related macular degeneration (AMD). Recent evidence suggests the retinal pigment epithelium (RPE) mitochondria to be the important cellular target of this oxidative stress.
Friday, February 24, 2006
Roger Steinert, MD, a member of our scientific advisory board and the current president of The American Society of Cataract and Refractive Surgery (ASCRS), explained in his ASCRS Binkhorst lecture, "The quest for perfect vision is the ultimate prize of our profession, but it's elusive and its very existence uncertain."
Friday, February 17, 2006
We are reaching out to ask our Friday Pearl readers to help with a legislative action on the FDAs refusal to protect your right to free speech. While guaranteed by the First Amendment, the FDA continues to place themselves above the law and censor nutrient-related disease prevention and treatment information, including statements as simple as "Vitamin C prevents scurvy", in spite of thousands of published peer-reviewed scientific studies that support dietary influence on chronic degenerative diseases.
Friday, February 10, 2006
It's appropriate this Friday before Valentine's Day to focus on a landmark study published this week in the Journal of the American Medical Association (JAMA), which finds that post menopausal women who consume a moderate fat diet are actually healthier and experience fewer chronic degenerative diseases, including breast and colon cancer and heart disease than those women who routinely consume very low fat diets.
Friday, February 03, 2006
A study published in the August 2005 Journal of Inflammation suggests that the proanthocyanidin activity in black currants can inhibit endothelial adhesion molecules (ICAM-1 and VCAM-1). The study also suggests that black currants can inhibit leukocyte (white cell) infiltration during inflammatory processes. The latter can be particularly important to the type of inflammation associated with chronic dry eye syndrome.
Friday, January 27, 2006
An important study funded by our friends at Research to Prevent Blindness and published in this month's British Journal of Ophthalmology suggests that men with a history of myocardial infarction or hypertension who take nitric oxide (NO) stimulating pharmaceutical drugs like Viagra or Cialis are putting themselves at risk of non-arteritic anterior ischemic optic neuropathy (NAION), which can lead to sudden partial blindness.
Friday, January 20, 2006
It has been demonstrated in peer-reviewed published studies that bovine lactoferrin, an antimicrobial glycoprotein included in the BioTears formulation, can inhibit adenovirus (a group of viruses that cause respiratory tract and eye infections). Lactoferrin has also been shown to exert its antiviral activity during the earliest phases of infection in a number of other viruses investigated to date. This is particularly important information given the current threat of viral diseases for which we have no vaccine.
Friday, January 13, 2006
Recent recommendations for the aggressive use of medications to lower low-density lipoprotein (LDL) cholesterol levels has contributed to a rising trend in the use of statin drugs. A study published in the January 2006 Archives of Ophthalmology evaluates the use of these drugs, specifically with regard to the risk of age-related macular degeneration (AMD).
Friday, January 06, 2006
The Journal of The American Medical Association (JAMA) published new data from the population-based prospective cohort Rotterdam Study in the December 28th 2005 issue titled The Dietary Intake of Antioxidants and Risk of Age-Related Macular Degeneration.