Friday Pearls

Friday Pearls

Fats: Matters of the Heart

Friday, February 10, 2006

It's appropriate this Friday before Valentine's Day to focus on a landmark study published this week in the Journal of the American Medical Association (JAMA), which finds that post menopausal women who consume a moderate fat diet are actually healthier and experience fewer chronic degenerative diseases, including breast and colon cancer and heart disease than those women who routinely consume very low fat diets.

Black Currants: Controlling Inflammation

Friday, February 03, 2006

A study published in the August 2005 Journal of Inflammation suggests that the proanthocyanidin activity in black currants can inhibit endothelial adhesion molecules (ICAM-1 and VCAM-1). The study also suggests that black currants can inhibit leukocyte (white cell) infiltration during inflammatory processes. The latter can be particularly important to the type of inflammation associated with chronic dry eye syndrome.

Optic Neuropathy and Nitric Oxide Stimulation

Friday, January 27, 2006

An important study funded by our friends at Research to Prevent Blindness and published in this month's British Journal of Ophthalmology suggests that men with a history of myocardial infarction or hypertension who take nitric oxide (NO) stimulating pharmaceutical drugs like Viagra or Cialis are putting themselves at risk of non-arteritic anterior ischemic optic neuropathy (NAION), which can lead to sudden partial blindness.

BioTears, Lactoferrin and Viruses

Friday, January 20, 2006

It has been demonstrated in peer-reviewed published studies that bovine lactoferrin, an antimicrobial glycoprotein included in the BioTears formulation, can inhibit adenovirus (a group of viruses that cause respiratory tract and eye infections). Lactoferrin has also been shown to exert its antiviral activity during the earliest phases of infection in a number of other viruses investigated to date. This is particularly important information given the current threat of viral diseases for which we have no vaccine.

Do Statins Increase AMD Risk?

Friday, January 13, 2006

Recent recommendations for the aggressive use of medications to lower low-density lipoprotein (LDL) cholesterol levels has contributed to a rising trend in the use of statin drugs. A study published in the January 2006 Archives of Ophthalmology evaluates the use of these drugs, specifically with regard to the risk of age-related macular degeneration (AMD).

A Look at the New JAMA ARED Nutrient Study

Friday, January 06, 2006

The Journal of The American Medical Association (JAMA) published new data from the population-based prospective cohort Rotterdam Study in the December 28th 2005 issue titled The Dietary Intake of Antioxidants and Risk of Age-Related Macular Degeneration.

2005 AAO Preferred Practice Pattern

Friday, December 30, 2005

The last Friday Pearl of the year addresses the 2005 American Academy of Ophthalmology's series of guidelines called Preferred Practice Patterns (PPP). These patterns identify characteristics and components of quality eye care for the purpose of detecting and diagnosing vision, health, or life-threatening disease.

Age-Related Vision Loss: The Lewin Report

Friday, December 16, 2005

The Lewin Group was commissioned in early 2005 by the Dietary Supplement Education Alliance (DSEA) to critically review the research literature concerning Omega-3 fatty acids, lutein and zeaxanthin. As the population lives longer, reducing the level of disability caused by age-related diseases is becoming more important. Activities central to independent living, which include reading, driving, and writing, are considerably impaired through the loss of central vision due to AMD.

Analysis of Nutrient Studies, Particularly the New Omega-3 Study

Friday, December 02, 2005

For the non-scientists, meta-analyses combine similar small studies together in an attempt to better assess the effects of a treatment. Meta-analyses are often considered the final word on the effects of those treatments, although there are serious limitations to this approach. When studies have different designs or inclusion parameters, deciding which studies to combine and which to leave out ...

Type 2 Diabetes, Alzheimer's and Macular Degeneration

Friday, November 18, 2005

A paradoxical effect of certain genes associated with type 2 diabetes, Alzheimer's and macular degeneration is linked in various studies to elevated homocysteine level, which is linked back to vitamin B6, B12 and folate deficiency. The oral insulin medications prescribed today for most type 2 diabetics is metformin and glyburide: both further inhibit normal absorption of vitamin B12 and folate.

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