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ZoOmega-3

ZoOmega-3

ZoOmega-3

Supplement Facts
 

Concentrated Pharmaceutical-Grade Fish Oil

  • Promotes a healthy body, including vascular system, heart, brain and retina
  • Molecularly distilled for high concentration of EPA and DHA
  • Supports healthy triglyceride levels
  • Supports the immune system
  • 60 capsule count per bottle
  • Recommended dosage: 1 or 2 capsules per day with meals 
  • Guaranteed to be mercury and PCB free
  • Made in the USA to FDA Good Manufacturing Standards (GMP).  
  • Full Money Back Guarantee - without exception
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ZoOmega-3 Product Information

Each capsule of ZoOmega-3 contains a 50% concentrate of pure pharmaceutical-grade oil from cold water fish. It is stabilized with 5 IUs of alpha tocopheryl Vitamin E and is guaranteed to contain no discernible amount of mercury, PCBs, cholesterol or triglycerides.
 . 
We always recommend that all fish oil capsules be consumed with a multiple that provides adequate antioxidants to address the metabolic oxidative stress associated with the retinal pigment epithelial (RPE), because it is one of the most active tissues in the body, and it includes the highest amount of Omega-3 DHA.

One capsule of ZoOmega-3 includes 300 mg of eicosapentaenoic acid (EPA) and 200 mg of docosahexanoic acid (DHA).  Each bottle of ZoOmega-3 contains 60 capsules. The recommended dosage is one or two capsules per day for optimal health, with a full-spectrum multiple for optimal Omega-3 fatty-acid/antioxidant balance.   Based on the most recent science, most doctors now recommend daily concentrated fish oil supplementation for those who do not eat cold water fish on a regular basis (at least twice a week).

The per mg cost of pharmaceutical-grade ZoOmega-3 EPA and DHA from concentrated fish oil is less than one third the per mg price of the EPA and DHA included in LOVAZA - the FDA approved pharmaceutical-grade 90% ethyl ester fish oil  concentrate - sold by prescription only.  
 

ZoOmega-3 Condition Overview

Years of over consumption of overly processed foods (mostly junk) has made the U.S. the least healthy country in the industrialized world. Fortunately for us, science has discovered that sufficient amounts of Omega-3 EPA and DHA from cold water fish oil will help balance, or neutralize some of the effects from the oils included in ALL processed cakes, cookies, chips, crackers, muffins, bagels, donuts, rolls, most breads and all fried foods.

However, taking fish oil does not mean that you can continue to consume large amounts of the above and expect to stay healthy.

Scientific Rationale for ZoOmega-3

A vast amount of scientific data supports fish oil supplementation for everyone, including children, because it contains the omega-3 essential fatty acids (EFAs), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). These long chain fatty acids are precursors to eicosanoids (site specific hormones, also referred to as signaling molecules) that reduce inflammation throughout the body including the eyes.
The long chain omega-3 fatty acids, EPA and DHA can be snythesized from plant- based omega-3 fatty acid alpha-linoleic acid (ALA), but EPA and DHA synthesis from ALA is not dependable in the best of circumstances. The capacity for conversion of ALA to DHA is higher in women than men. Studies of ALA metabolism indicate that approximately only 8% of dietary ALA is converted to EPA and 0-4% is converted to DHA in healthy young men. In healthy young women, approximately 21% of dietary ALA is converted to EPA and 8% is converted to DHA. (1-2)
This is particularly important information for those people who insist on using or recommending Flax Seed Oil as a source of Omega-3 fatty acids.

In a scientific statement called Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease, the American Heart Association stated, "The EPA and DHA form of omega-3 found in fish oil can have a therapeutic role in the treatment of very high triglycerides, and both EPA and DHA have triglyceride-lowering properties." (3)
  • There is now a considerable factual basis from laboratory and clinical trials that omega-3 fatty acids from fish oil will help prevent fatal arrhythmias in animals and humans. (3)
  •  EPA and DHA from fish oil is suggested in a number of studies to prevent or slow the progression of many degenerative diseases associated with elevated plasma levels of triglycerides. (3)
  • Long chain Omega-3 fatty acids from fish oil and vitamin A palmitate are suggested to slow the progression of Retinitis pigmentosa. (4)
  • Primary open-angle glaucoma patients are suggested to have reduced levels of blood EPA and DHA. (5)
  • Long chain Omega-3 fatty acids are suggested to slow the progression of of neurodegenerative and retina diseases including macula degeneration. (6-12)
  • Regulation of Gene Expression

The results of cell culture and animal studies indicate that omega-6 GLA and omega-3 fatty acids EPA /DHA can modulate the expression of a number of genes, including those involved with fatty acid metabolism and inflammation. (13-14)

References:

 
7. Neuroprotection D1 (NPD10): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Bazan NG. Brain Pathol. 2005 Apr;15(2):159-66 [abstract]
1. Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men. Burdge GC, Jones AE, et al. Br J Nutr. 2002;88(4):355-364 [abstract]
2. Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Burdge GC, Wootton SA. Br J Nutr. 2002;88(4):411-420 [abstract]
3. Anti-arrhythmic properties of N-3 poly-unsaturated fatty acids (n-3 PUFA). Lombardi F, Terranova P. Curr Med Chem 2007;14(19):2070-80 [abstract]
4. Retinitis pigmentosa. Hartong DT, Berson EL, Dryja TP Lancet 2006 Nov 18;368(9549):1795-809. [abstract]
5. The role of omega-3 long-cahin polyunsaturated fatty acids in health and disease of the retina.SanGiovanni JP, Chew EY. Prog Retin Eye Res. 2005 Jan;24(1):87-138 [abstract]
6. Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors.Bazan NG, Trends in Neurosciences 2006 May;29(5):263-71 [abstract]
8. Application of nutrigenomics in eye health. Delcourt C. Forum Nutrition 2007;60:168-75 [abstract]
9. Photoreceptor outer segment phagocytosis attenuates oxidative streee-induced apoptosis with concomitant neuroprotectin D1 synthesis. Mukherjee PK, Marcheselli VL, et al. Proc National Acad Sci 2007 Aug 7:104(32):13158-63 [abstract]
10. Increased dietary intake of omega-3 polyunsaturated fatty acids reduces pathological retinal angiogenesis. Connor KM, SanGiovanni JP, Lofqvist C, et al. Nat Med 2007Jul;13(7):868-73 [abstract]
11. Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection. Bazan NG Curr Opin Clin Nutr Metab Care 2007 Mar;10(2):136-41 [abstract]
12. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD Cangemi FE BMC Ophthalmol 2007 Feb 26:7:3 [abstract]
10. Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection. Bazan NG Curr Opin Clin Nutr Metab Care 2007 Mar;10(2):136-41 [abstract]
13.Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae / lipid rafts by docosahexaenoic acid. Chen W, Jump DB, et al. Invest Ophthalmol Vis Sci. 2007Jan;48(1):18-26 [abstract]
14. Effects of EPA, DHA on the secretion of NO, expressions of iNOS mRNA and DNA-binging activity of NFkappyB in human monocyte Xia Y, Feng X, Chen Y, SuY, Wei Sheng Yan Jiu 2007 Jul;36(4):445-8 [abstract]
  • QWhy does fish oil repeat itself in some people?

    If you get a fishy taste in your mouth after taking fish oil capsules, the product may very well be rancid. Although there is a small percentage of the population who seem to have a low GI tolerence for fish oil. All fish oil products must be stabilized with Vitamin E, since these oils have an extremely short shelf life without it. Unfortunately, fish oil and most vegetable oils, including Flax Seed Oil, become pro-oxidants if they become rancid and these pro-oxidants wreack havoc with our health. Each capsule of ZoOmega-3 is stabilized with 5 IUs of Vitamin E.

  • QWhat should I look for in a fish oil product?

    With fish oil, like most everything else, you tend to get what you pay for, with the exception being the prescription-only fish oil called OMACOR (lovastin), which sells for $120.00 for a one month supply (more than three times the per mg cost of EPA/DHA in ZoOmega-3). We suggest you look for ethyl concentrated EPA/DHA pharmaceutical-grade fish oils from reputable companies that will guarantee their product is from cold water fish, and free of mercury and PCBs. ZoOmega-3 meets these requirments

  • QWhy is everyone so excited about fish oil?

    Years of over-consumption of overly-processed junk food has made the U.S. the least healthy country in the industrialized world. Fortunately for us, science has discovered that sufficient amounts of Omega-3 EPA and DHA from cold water fish oil can nutralize some of the vascular damage created by the cooking oils included in most ALL processed foods including cakes, cookies, chips, crackers, muffins, bagels, donuts, breads, fried foods and margarine. Fish oil is also associated with improved joint health, better behavior, and improved eye health. However, taking fish oil supplements does not mean that you can continue to consume large amounts of the above and stay healthy.

  • QWhat does ZoOmega-3 mean?

    ZoOmega is a combination of two words: zoology, which is the biological discipline that involves the study of non-human animals (ncluding fish) and Omega-3, which is a family of polyunsaturated fatty acids - the important ones being alpha-linolenic-acid (ALA) from plants and eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are downstream metabolites of plant-based ALA. Both EPA and DHA are more readily available from fish than from plant-based Omega-3s - including flax seed oil.

  • QShould I take ZoOmega-3 if I take BioTears?

    BioTears is specifically designed to address mucosal tissue health. It has been suggested in clinical studies and case reports to be effective on a large percentage of dry eye sufferers. However, in a few cases, additional EPA /DHA from one or two daily capsules ZoOmega-3 has improved effectivness.

  • QIs ZoOmega-3 an ethyl ester form of fish oil, or a TG form?

    ZoOmega-3 is produced through molecular distillation during the manufacturing process. Since triglycerides do not fractionate well, they are first transformed to ethyl esters and then fractionated. This assures an exceptionally clean source of omega-3 fatty acids. No one has presented peer-reviewed and published science to support the claim being made by some companies that the TG form of fish oil is “300% more absorbable than ethyl ester forms. At this point there is no science to suggest that the ethyl ester form of fish oil to be toxic either. In fact, the FDA approved Omacor, which is also an ethyl ester highly concentrated fish oil, because their studies proved it to be effective and completely safe. Omacor is being sold as a pharmaceutical because some insurance companies will cover the $120 per month cost as a pharmaceutical dru

  • QWhere does the fish in ZoOmega-3 come from?

    The fish in ZoOmega-3 fish oil capsules come from Northern Atlantic cold waters. However, that questions does not really give us much information since fish oil sellers use it to make claims about competitors that may not be true. ConsumerLabs tested 55 different brands of over-the-counter fish oil last year and not one of them contained mercury (we do a good job of not allowing mercury laden fish oil into this country). The only fish oil they found problems with was the Kirkland Brand from Costco. This brand did not fail the mercury test, it failed enteric coating test and it included the amount of Omega-3 EPA/DHA listed on the label.